The pressure up in the air is much less than the pressure on the ground. The pressure inside the aeroplane is artificially kept similar to the pressure on the ground. So if there is a whole in the plane while it is high up in the air, for example because someone opened a window or door, there would be a big difference between the pressure inside and the pressure outside. This means the air would rush from inside to outside, blowing everything else out with it.
Yes, because an aeroplane is travelling so fast and the air pressure is low outside, air will rush from inside the cabin (which is pressurised) outside, sucking objects along with it.
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